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Identification of patients with coronary disease at high risk for loss of employment: A prospective validation study
Circulation, 1992, Volume 86 (Number 5), Seite 1485-1494, Dallas, Texas: Eigenverlag, ISSN: 0009-7322
Methods and results:
This model was then validated in the independent prospective test sample (380 patients enrolled between March 1989 and June 1990). Eight factors were independent predictors of departure from the work force: lower initial functional status (as assessed by the Duke Activity Status Index), followed by older age, black race, presence of congestive heart failure, lower education level, presence of extracardiac vascular disease, poorer psychological status, and lower job classification. Standard clinical variables provided only 20% of the total predictive information available from the model about follow-up work outcomes, whereas functional measures provided 27%, and demographic and socioeconomic measures provided 45%. In the test sample, the area under the receiver operating characteristic curve for the model predictions was 0.74, compared with 0.80 in the training sample, and model predictions agreed well with observed prevalences of return to work. After adjustment for baseline imbalances, there was no significant differenc e in 1-year return-to-work rates among the patients receiving initial PTCA or CABG therapy versus initial medical therapy.
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